Biotechnology

원문 링크: https://www.nature.com/articles/s41598-018-31080-7 파일 링크: [Title] Application of the fragment molecular orbital method to discover novel natural products for prion disease [Abstract] Conformational conversion of the normal cellular isoform of the prion protein PrPC into an infectious isoform PrPSc causes pathogenesis in prion diseases. To date, numerous antiprion compounds have been devel..